Human TGF-beta receptor type-1 (TGFBR1) ELISA Kit

From Assay Genie, this Sandwich ELISA kit enables quantitative detection of human TGF-beta receptor type-1 (TGFBR1) in serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids. It provides a detection range of 0.156-10ng/mL with a sensitivity of 0.078ng/mL.

TGFBR1 is a transmembrane serine/threonine kinase that pairs with the type II receptor TGFBR2 to transduce TGF-beta signals, regulating processes such as cell proliferation, differentiation, wound healing, extracellular matrix production, and immunosuppression. Dysregulation of this pathway is implicated in cancer, fibrosis, and immune disorders, supporting its value as a research biomarker. The kit reports an intra-assay CV of 4.9% and an inter-assay CV of 9.0%, with recovery of 94-106% in serum and 96-108% in plasma.

Synonyms for the target include ALK-5, ALK5, SKR4, TGFR-1, Activin receptor-like kinase 5, TGF-beta type I receptor, and Transforming growth factor-beta receptor type I. The kit is for research use only and is associated with UniProt entry P36897.