Human TELO2 ELISA Kit (HUFI06145)

Quantify human TELO2 protein expression levels using this ELISA kit from Assay Genie. TELO2 operates as a scaffolding component of the TTT (Tel2-Tti1-Tti2) complex, where it stabilises PIKK-family kinases such as ATM, ATR, DNA-PKcs and mTOR that govern DNA damage response and telomere maintenance. The product supports research into telomere biology, checkpoint signalling and the rare developmental disorder You-Hoover-Fryns syndrome, in which biallelic TELO2 variants produce intellectual disability, intrauterine growth restriction and brain malformations.

Its plate-based protocol delivers an in vitro absorbance readout, appropriate for laboratory workflows ranging from cell culture supernatant analysis to tissue lysate profiling. Each kit contains all reagents for the indicated number of determinations, supplied in single-use vial format and intended for refrigerated storage at -20 degrees C until first use; aliquots remain stable frozen at -80 degrees C for long-term retention.

Intended strictly for research use only, the assay complements western blot and PCR approaches when characterising PIKK pathway activity in cancer, ageing and neurodegeneration studies.