Human TEK Tyrosine Kinase, Endothelial (Tie2) ELISA Kit

The receptor tyrosine kinase TEK, also called Tie2, is a central regulator of vascular development and blood vessel stability, expressed predominantly on endothelial cells and on subsets of hematopoietic stem cells. Signaling through TEK is triggered by the angiopoietin ligands and is implicated in tumor angiogenesis, inflammatory vascular remodeling, and cardiovascular pathology, including venous malformations associated with germline TEK mutations.

This quantitative ELISA kit from Assay Genie enables researchers to measure human TEK protein concentrations across multiple biological matrices, supporting studies in vascular biology, oncology, regenerative medicine, and cardiovascular research. The assay is intended for research use only and ships as a complete reagent set, with standards, detection antibodies, and buffers sufficient for ninety-six reactions in a single kit. Compatible specimens include human serum fractions, plasma samples, prepared tissue homogenates, and cell lysates, allowing flexible study designs across patient cohorts and cell-based models.

Procedures follow standard microplate workflows compatible with routine laboratory readers, and the assay has been validated specifically for the measurement of human TEK. By providing a quantitative readout of Tie2 levels, the kit allows investigators to explore the angiopoietin-Tie2 signaling axis in disease models and to assess the impact of experimental or therapeutic interventions on endothelial receptor expression.