Human TEK/Tie-2 (Angiopoietin Receptor Tie2) ELISA Kit (HUFI07678)

The Assay Genie human Tie-2 ELISA kit provides researchers with a quantitative immunoassay tool for measuring angiopoietin receptor Tie-2 (also known as TEK) in human biological specimens. Tie-2 is an endothelial receptor tyrosine kinase activated by the angiopoietin ligands Ang-1 and Ang-2, and it plays a central role in vascular remodeling, blood vessel maturation, and angiogenic signaling cascades. Quantifying circulating or tissue-derived Tie-2 levels supports investigations into tumor angiogenesis, cardiovascular pathophysiology, diabetic vascular complications, sepsis-related endothelial dysfunction, and pulmonary hypertension research.

Supporting laboratory research workflows, the kit enables studies of receptor-ligand interactions within the angiopoietin-Tie signaling axis, allowing researchers to explore how Tie-2 expression changes in disease models or under experimental treatment conditions. Tie-2 measurements are frequently used alongside Ang-1 and Ang-2 assessments to characterize angiogenic balance in cell culture supernatants, tissue lysates, and clinical research specimens.

Each kit includes reagents packaged for the stated assay size, with all components supplied in individual vials. Standard laboratory equipment including a microplate reader capable of measuring absorbance is required. Researchers should consult the product insert for detailed protocol information, including recommended sample preparation, dilution guidelines, and assay procedure. The kit is labeled for research use only.

Research Applications:

• Angiogenesis and vascular biology studies in oncology and tumor microenvironment research
• Cardiovascular disease models examining endothelial signaling
• Sepsis and inflammatory endothelial dysfunction investigations
• Characterization of Tie-2, Ang-1, and Ang-2 ligand-receptor balance in vitro and in vivo
• Biomarker profiling in pulmonary hypertension and diabetic vascular complications

Key Features:

• Targets human Tie-2 (TEK), the angiopoietin receptor central to endothelial and angiogenic signaling
• Quantitative immunoassay platform from Assay Genie for vascular biology, oncology, and cardiovascular research
• Reagents provided in vials for the stated assay size
• Intended for research use only, not for diagnostic procedures