Human TCN2/Transcobalamin-2 ELISA Kit

Designed for the accurate measurement of Transcobalamin-2 (TCN2) levels in human samples, this double-antibody sandwich ELISA from Assay Genie offers high sensitivity and specificity for a variety of research applications. TCN2, also known as vitamin B12-binding protein, plays a crucial role in vitamin B12 transport in the bloodstream, and dysregulation of TCN2 has been associated with vitamin B12 deficiency, anemia and nerve damage, making the kit a useful tool for biomarker studies and therapeutic development.

The assay is reactive with human samples and accepts serum, plasma, cell culture supernatant, cell or tissue lysate, and other liquid samples. Detection is TMB-based, with absorbance read at 450 nm, and the kit is intended for storage at 2-8°C for 12 months.

Performance specifications include a sensitivity of 75 pg/mL and a detection range of 125-8000 pg/mL. Linearity across 1:2 to 1:8 dilutions is 94-100% in serum, 90-105% in EDTA plasma and 86-101% in heparin plasma, with mean recovery of 95% in serum, 96% in EDTA plasma and 96% in heparin plasma. The kit is associated with UniProt entry P20062 within the Signal Transduction research area.