Human TBX15 (T-box transcription factor TBX15) ELISA Kit (HUFI06179)

TBX15 encodes a T-box family transcription factor with established roles in skeletal morphogenesis, craniofacial development, and the specification of brown adipose tissue from mesenchymal precursors. Pathogenic variants in TBX15 underlie Cousin syndrome, an autosomal-recessive skeletal dysplasia characterized by short stature, facial dysmorphism, and abnormal pelvic morphology, making quantitative protein-level measurement of TBX15 relevant for developmental biology, metabolic research, and rare disease investigations.

Assay Genie's immunoassay is configured around a human-specific capture antibody and is intended for research use only. The kit is supplied with a pre-coated microplate, biotinylated detection reagent, streptavidin-HRP conjugate, wash concentrate, calibrated standards, chromogenic substrate, and stop solution, providing all reagents needed for one full plate of unknowns, calibrators, and internal controls.

For optimal performance, aliquot specimens upon collection and store the kit components refrigerated at 4°C; freeze unused clinical aliquots at -80°C and avoid repeated freeze-thaw cycles to preserve epitope integrity. Researchers commonly pair this ELISA with downstream western blot or immunohistochemistry workflows on patient-derived fibroblasts, osteoblast lineages, or adipose-derived stem cells to corroborate TBX15 expression patterns.