Human TBR1 ELISA Kit (HUFI06188)

The Assay Genie Human TBR1 ELISA Kit supports research use only workflows for in vitro quantitative measurement of T-box brain transcription factor 1 (TBR1) in human serum specimens. TBR1 is a member of the T-box gene family expressed in post-mitotic glutamatergic projection neurons of the developing cerebral cortex, hippocampus, and amygdala, where it guides cortical lamination, axon pathfinding, and AMPA-receptor gene regulation. Reduced or disrupted TBR1 function has been associated with autism spectrum disorder, intellectual disability, and cortical malformation syndromes, which is why neuroscience and developmental-biology groups target this protein in biomarker discovery projects.

Each package contains a pre-coated microplate, calibrated protein standards, biotinylated detection reagent, enzyme conjugate, wash buffer concentrate, and substrate solution, supplied as a complete ready-to-use kit. Components should be stored refrigerated; allow all reagents to equilibrate to room temperature before opening, and limit freeze-thaw cycles of diluted standards to preserve binding activity. Researchers commonly pair this ELISA with western blot or immunohistochemistry follow-up experiments to validate TBR1 expression in matched cell or tissue lysates.