Human TBCK (TBC domain-containing protein kinase-like protein) ELISA KIT (HUFI04829)

TBCK (TBC domain-containing protein kinase-like protein) is a Rab GTPase-activating protein implicated in TBCK-related encephalopathy, a recessive neurodevelopmental disorder. Loss of TBCK function disrupts mTORC1 signaling and autophagy flux, contributing to infantile hypotonia, psychomotor delay, and progressive neurodegeneration. This Assay Genie ELISA enables quantitative detection of human TBCK, with a typical detection range of 0.156-10 ng/mL, supporting applications in disease modeling, biomarker discovery, and pathway analysis.

The 96 Assays kit is supplied with a pre-coated microplate and reagents sufficient for laboratory research use only. Each well uses 100 µL of sample; unopened components should be stored refrigerated, while reconstituted standards are best aliquoted and frozen to limit freeze-thaw cycles, preserving binding activity across the shelf life of the kit.