Human TARS/Threonyl tRNA Synthetase, cytoplasmic ELISA Kit

Assay Genie offers a Sandwich ELISA, Double Antibody kit designed for the accurate quantification of human TARS (Threonyl-tRNA Synthetase, cytoplasmic) in serum, plasma, cell culture supernatant, cell or tissue lysate, and other liquid samples. The assay uses a colorimetric detection method and is grouped under the Metabolism research area, with TARS (UniProt P26639) listed as the target synonym.

Key performance characteristics quoted from the product specification include a sensitivity of 0.188 ng/mL and an assay range of 0.313-20 ng/mL. Reported linearity at 1:2, 1:4 and 1:8 dilutions covers Serum (n=5) 85-102% / 83-100% / 89-100%, EDTA Plasma (n=5) 89-103% / 82-100% / 80-98% and Heparin Plasma (n=5) 92-103% / 83-100% / 82-96%. Recovery data: Serum (n=5) 87-102% with average 97%, EDTA Plasma (n=5) 87-104% with average 93%, and Heparin Plasma (n=5) 95-104% with average 100%. The kit is stored at 2-8°C for 12 months.

TARS is described as an essential enzyme involved in protein synthesis, specifically attaching threonine to its cognate tRNA molecule. Dysregulation of TARS has been linked to cancer, neurological disorders and metabolic diseases, making it a biomarker of research interest for studying its role in health and disease.