Human T-lymphocyte activation antigen CD80 (CD80) ELISA Kit

Designed for the precise quantification of human T-lymphocyte activation antigen CD80, this Sandwich ELISA Kit from Assay Genie is a high-quality colorimetric assay. It reacts with human samples, supporting research into CD80, a co-stimulatory molecule involved in T-lymphocyte activation whose abnormal expression has been implicated in autoimmune diseases, transplant rejection, and inflammatory conditions.

The kit detects natural and recombinant human CD80 across a range of 78-5000pg/mL, with a sensitivity of 20pg/mL. Reported precision values include an intra-assay CV of 6.4% and an inter-assay CV of 7.9%. It is intended for serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, and is for research use only within the immunology field.

CD80 is a single-pass type I membrane protein (UniProt P33681, molecular weight 18,761 Da; NCBI Gene ID: 941) that provides the costimulatory signal essential for T-lymphocyte activation: T-cell proliferation and cytokine production are induced by CD28 binding, while CTLA-4 binding has the opposite effect and inhibits T-cell activation.