Human T-Cell, Immune Regulator 1 (TCIRG1) ELISA Kit

Encoded by TCIRG1 and originally characterized in activated T lymphocytes, T-Cell Immune Regulator 1 is the a3 subunit of the vacuolar H⁺-ATPase proton pump central to osteoclast function. Biallelic loss-of-function mutations in this gene are the most common cause of autosomal recessive osteopetrosis, and altered expression has been reported in dendritic cells and other immune populations. Researchers investigating bone remodeling, V-ATPase biology, and inherited skeletal disorders can quantify TCIRG1 protein in human research samples with this Assay Genie ELISA kit. The microplate-based assay is supplied ready to use for in vitro studies, with components stored refrigerated until first use. Reconstituted standards should be aliquoted to limit freeze-thaw cycles, and the kit is intended for research use only.