Human SYNGAP1 (Synaptic Ras GTPase-activating protein 1) ELISA Kit (HUFI06237)

Quantitative analysis of human SYNGAP1, a neuronal Ras GTPase-activating protein central to postsynaptic Ras-MAPK signaling and the maturation of excitatory synapses, is supported by this 96 Assays research kit from Assay Genie. Loss-of-function variants in SYNGAP1 are linked to intellectual disability, autism spectrum disorder, and early-infantile epileptic encephalopathy, so reliable protein quantification is valuable for translational neuroscience studies, biomarker discovery in patient cohorts, and mechanistic work on synaptic dysfunction.

The configuration supplies microplate-based reagents, calibrated standards, and detection antibodies for absorbance-based measurement in human-derived serum specimens or plasma specimens. Applications include profiling expression changes in cell or animal models, screening samples from individuals carrying SYNGAP1 mutations, and characterizing regulators of AMPA receptor trafficking at the postsynaptic density. The kit is intended for research use only and supports in vitro laboratory workflows; users should follow the supplied protocol for sample preparation, incubation times, and plate reader settings.

Unopened components should be stored refrigerated and protected from light until first use. Reconstituted reagents and diluted standards should be aliquoted to limit freeze-thaw cycles and preserve assay performance across experimental runs.