Human Suppressor Of Zeste 12 Homolog (SUZ12) ELISA Kit

Built for epigenetics and chromatin biology research, this Assay Genie immunoassay quantifies human Suppressor Of Zeste 12 Homolog (SUZ12), a core scaffolding subunit of the Polycomb Repressive Complex 2 (PRC2) that catalyzes trimethylation of histone H3 at lysine 27 (H3K27me3) to silence developmental and tumor-suppressor target genes. Investigators studying X-chromosome inactivation, embryonic stem cell pluripotency, lineage commitment, or PRC2 dysfunction apply the kit to measure SUZ12 protein abundance in tissue homogenates. Each pack provides reagents sufficient for 96 determinations run on a standard microplate reader with an absorbance-based colorimetric readout. The product supports in vitro studies into SUZ12 loss-of-function and overexpression in endometrial carcinoma, breast cancer, and glioma, where altered PRC2 activity has been documented. Reagents should be aliquoted and stored per the enclosed insert to preserve activity across the kit shelf life; the assay is intended for research use only.