Human Suppressor of cytokine signaling 2 (SOCS2) ELISA Kit

A Sandwich ELISA Kit from Assay Genie designed for the quantitative measurement of human Suppressor of Cytokine Signaling 2 (SOCS2) in serum and plasma samples. The assay uses a colorimetric detection method, is reactive with human samples, and is intended for research use only.

Manufacturer specifications indicate a detection range of 125-8000pg/mL with a sensitivity of 56pg/mL. Intra-assay CV is reported at 3.8% and inter-assay CV at 7.4%. Recovery in serum ranges from 80-90% with an average of 84%, and plasma recovery ranges from 80-92% with an average of 86%. The kit recognises natural and recombinant human SOCS2 and supports research in the field of immunology.

SOCS2 belongs to the suppressor of cytokine signaling family and acts as a negative regulator of cytokine signal transduction, particularly within the growth hormone/IGF1 signaling pathway. Dysregulation of SOCS2 has been linked to autoimmune disorders, cancer, and metabolic syndromes, making it a relevant biomarker for studies into disease mechanisms and potential therapeutic targets.