Human SUOX ELISA Kit (HUFI06253)

Researchers investigating disorders of sulfur amino acid catabolism rely on quantitative immunoassay tools to measure sulfite oxidase, and the Assay Genie Human SUOX ELISA Kit addresses this need in a 96 Assays microplate format configured for in vitro detection of the molybdenum-containing mitochondrial enzyme.

SUOX catalyzes the terminal oxidation of sulfite to sulfate, the final step in metabolism of sulfur derived from cysteine and methionine. The enzyme operates in the mitochondrial intermembrane space, and reduced SUOX activity is a hallmark of isolated sulfite oxidase deficiency as well as molybdenum cofactor deficiency. Both conditions present with severe neonatal neurological impairment, including intractable seizures, encephalopathy, and progressive neurodegeneration, making accurate quantification of SUOX valuable for disease mechanism research, biomarker discovery, and translational studies of inborn errors of metabolism.

The kit supports broader investigation into mitochondrial oxidative pathways and oxidative stress biology, where altered sulfite handling has been linked to cellular damage in neurological and renal tissues. Reconstituted standards and prepared samples are handled under standard laboratory conditions, with refrigerated storage recommended to preserve antibody binding activity and ensure reproducible performance across multiple analytical runs.