Human Succinate Dehydrogenase Complex Subunit A (SDHA) ELISA Kit

Quantitatively measure succinate dehydrogenase complex subunit A in human research samples with the Assay Genie ELISA Kit. SDHA is the flavoprotein subunit of mitochondrial complex II, anchoring the enzyme to the inner mitochondrial membrane and participating directly in electron transfer to ubiquinone during the TCA cycle. Researchers studying mitochondrial bioenergetics, oxidative phosphorylation defects, and metabolic reprogramming in tumor cells rely on this kit to assess SDHA protein abundance across cell lysates and tissue homogenates.

Each kit provides reagents sufficient for 96 determinations and is read on a standard microplate reader, supporting medium-throughput studies comparing patient-derived samples, knockout cell lines, or treatment cohorts.

Research applications include:

• Characterizing complex II deficiency in hereditary paraganglioma-pheochromocytoma syndromes and Leigh syndrome
• Tracking mitochondrial content across cancer cell line panels
• Evaluating respiratory chain perturbations in neurodegeneration models
• Validating CRISPR or siRNA knockdown efficiency of SDHA in vitro