Human STXBP5 ELISA Kit (HUFI06269)

Quantitative measurement of endogenous human syntaxin-binding protein 5 is supported by this immunoassay kit from Assay Genie, validated for use with human specimen types in research applications spanning SNARE-dependent vesicle fusion. STXBP5, also known as tomosyn-1, negatively regulates SNARE complex assembly and modulates vesicle priming across multiple cell types.

The protein has been studied in the context of insulin granule exocytosis in pancreatic beta cells, neurotransmitter release at presynaptic nerve terminals, and platelet dense-granule secretion, with genome-wide association studies linking STXBP5 variants to type 2 diabetes risk, glycated hemoglobin levels, and certain neurological conditions including epilepsy.

The assay relies on an enzymatic color change detectable by standard microplate readers and is configured for a full plate run with all necessary reagents, plates, and buffers provided. Application areas include endocrinology, neuroscience, and metabolic disease research, where accurate protein-level quantification complements genetic and cellular investigations. Each kit is intended for research use only.