Human Stromelysin-2 (MMP10) ELISA Kit

A sandwich ELISA from Assay Genie for the accurate quantification of Human Stromelysin-2 (MMP10) in human serum, plasma, tissue homogenates, cell culture supernatants, and other biological fluids. MMP10 (Stromelysin-2) is an enzyme involved in extracellular matrix degradation and tissue remodeling, and its dysregulation has been associated with cancer, arthritis, and cardiovascular conditions, making it a useful biomarker in research.

Key performance figures include a detection range of 78-5000pg/ml and a sensitivity of 32pg/mL. The intra-assay CV is 4.7% and inter-assay CV is 9.8%. Recovery averages 94% (range 88-100%) for serum and 96% (range 90-102%) for plasma. The assay is specific for natural and recombinant human Stromelysin-2 and is for research use only, with applications in the cancer research area.

Synonyms include Matrix metalloproteinase-10, Transin-2, MMP-10, SL-2, and STMY2. The target protein (UniProt P09238) can degrade fibronectin, gelatins of type I, III, IV, and V, and weakly degrade collagens III, IV, and V, and it activates procollagenase.