Human sTNFRII PharmaGenie ELISA Kit (SBRS1169)

This ELISA from Assay Genie quantitatively measures human soluble Tumor Necrosis Factor Receptor II (sTNFRII), a shed extracellular decoy receptor that buffers circulating TNF-α and serves as a biomarker of systemic inflammation. The assay supports research into autoimmune conditions, sepsis, chronic kidney disease, and inflammatory cytokine networks, where altered sTNFRII/TNF ratios often correlate with disease activity and outcomes. Researchers can profile sTNFRII release in cell culture models and in donor-matched biospecimens to investigate TNF pathway regulation, immune cell signaling, and pharmacologic modulation of the TNF axis.

Each kit provides pre-coated microplate wells, detection antibody, calibrator standards, and reagents sufficient for the full plate; a 100 µL sample volume is recommended per well. Antibody and conjugate components should be stored refrigerated and protected from light, while reconstituted standards require aliquoting and freezing with limited freeze-thaw cycles.