Human STK3 (Serine/threonine-protein kinase 3) ELISA Kit (HUFI06291)

Serine/threonine-protein kinase 3 (STK3), also called MST2, is a core kinase of the Hippo tumor suppressor signaling cascade, phosphorylating downstream LATS1/2 to restrain YAP/TAZ-driven transcription. The Assay Genie Human STK3 ELISA Kit offers a quantitative immunoassay platform for measuring STK3 protein abundance in human samples.

Researchers investigating Hippo pathway regulation, contact inhibition, organ size control, and apoptosis induction use STK3 quantification to characterize kinase activity and pathway flux. This 96 Assays format kit supports cancer biology work, including hepatocellular carcinoma, breast cancer, and colorectal cancer models where STK3/MST2 expression is frequently altered. Additional applications include studies of oxidative stress, where caspase-mediated cleavage of STK3 inactivates the kinase and shifts cellular fate, as well as investigations of cardiac development, immune cell signaling, and regenerative biology.

Each kit ships with all components required to perform the assay, including pre-coated microplate wells, detection antibodies, recombinant standards, diluents, wash buffer, and substrate in individual vials. Intended for research use only in academic, pharmaceutical, and biotechnology laboratories focused on cell signaling, tumor biology, and kinase-targeted drug discovery. Store unopened reagents according to manufacturer instructions and equilibrate to room temperature before beginning the protocol.