Human STIM1 ELISA Kit (HUFI08420)

This immunoassay from Assay Genie enables quantitative measurement of STIM1 in human serum and plasma samples, using a pre-coated 96-well microplate format. STIM1 (Stromal Interaction Molecule 1) is an endoplasmic reticulum calcium sensor that activates ORAI1 channels to mediate store-operated calcium entry, a process central to immune signaling, platelet activation, and skeletal muscle contraction. The procedure requires approximately 100 uL of sample per well, with a colorimetric readout compatible with standard plate readers. Researchers use this kit to investigate calcium signaling dysregulation linked to immunodeficiency, autoimmunity, and Stormorken syndrome, conditions in which altered ER calcium homeostasis contributes to disease pathogenesis.