Human Sterol regulatory element-binding protein 2 (SREBF2) ELISA Kit

This sandwich ELISA from Assay Genie is designed for the quantitative measurement of Human Sterol regulatory element-binding protein 2 (SREBF2) in human samples including serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. SREBF2 is a key transcription factor involved in the regulation of cholesterol and fatty acid metabolism, and its dysregulation has been implicated in metabolic disorders such as dyslipidemia, obesity, and cardiovascular diseases, making precise quantification relevant to research in lipid homeostasis and related disease pathways.

The kit uses an ELISA detection method with a stated detection range of 0.312-20ng/mL and a sensitivity of 0.12ng/mL. Intra-assay precision is reported as 5.6% CV and inter-assay precision as 8.3% CV. The assay is specific for natural and recombinant human Sterol regulatory element-binding protein 2 (UniProt Q12772) and is intended for research use only within the cardiovascular research area.

Dilutional linearity is reported for serum, EDTA plasma and heparin plasma across 1:2 to 1:16 dilutions, and spike-and-recovery values are reported for serum (average 89%, range 83-95%) and plasma (average 91%, range 85-97%).