Human Stem Cell Factor Receptor (SCFR) ELISA Kit

Assay Genie's immunoassay panel quantitatively measures human Stem Cell Factor Receptor (SCFR), also known as c-KIT or CD117, a 145 kDa type III receptor tyrosine kinase encoded on chromosome 4q12 that binds stem cell factor (SCF/KITLG) and drives signaling in hematopoietic stem cells, mast cells, melanocytes, germ cells, and interstitial cells of Cajal. Investigators working on hematopoiesis, mast cell biology, melanocyte development, gametogenesis, or KIT-driven oncogenesis — including gastrointestinal stromal tumors, systemic mastocytosis, and acute myeloid leukemia — deploy this ELISA to quantify receptor levels across multiple human specimen matrices. The validated protocol accepts serum-based preparations, plasma-derived samples, tissue homogenates, cell lysates, and cell culture supernatants, enabling studies of receptor shedding, tumor expression profiling, and conditioned media analysis from engineered cell lines. Each 96 assays packaging supports moderate-throughput screening, and the colorimetric endpoint is read on a standard microplate reader. Reagents should be kept refrigerated until first use and protected from light. This research-use-only product is intended for laboratory investigation of KIT pathway biology in human specimens, not for clinical diagnostic procedures.