Human STAG1 ELISA Kit (HUFI06306)

The assay targets STAG1 (Stromal Antigen 1), a core component of the cohesin ring complex that tethers sister chromatids following DNA replication and supports accurate chromosome segregation during mitosis. It also participates in DNA double-strand break repair and in transcriptional regulation through loop extrusion. Researchers deploying this kit explore STAG1 abundance in circulating biofluid samples in the context of cohesinopathies such as Cornelia de Lange syndrome, where heterozygous STAG1 mutations have been identified. Additional applications include cancer biomarker investigations, where altered STAG1 expression and copy-number variation have been reported in myeloid neoplasms and several solid tumor types. The quantitative immunoassay plate supplied by Assay Genie comes as a complete reagent set with pre-coated microplate wells, lyophilised standards, biotinylated detection antibody, streptavidin-HRP conjugate, wash buffer, substrate solution, and stop reagent sufficient for a full plate run. Reagents are intended for research use only in vitro, and absorbance readouts enable interpolation of unknown concentrations against a generated standard curve.