Human ST8SIA2 ELISA Kit (HUFI08429)

The Assay Genie human ST8SIA2 ELISA Kit enables quantitative measurement of ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 in human research specimens. ST8SIA2 is a Golgi-resident glycosyltransferase that drives polysialylation of neural cell adhesion molecules, a post-translational modification central to neuronal migration, axon guidance, and synaptic plasticity during brain development.

This colorimetric immunoassay targets the human ST8SIA2 protein and is configured for research use only, making it a practical tool for laboratories investigating neurodevelopmental biology and pathways associated with schizophrenia and bipolar disorder. Each kit contains reagents sufficient for 96 Assays in a microplate format, supporting mid-throughput screening of cell culture supernatants, tissue homogenates, and other biological matrices relevant to sialylation research.

Beyond neuroscience applications, the kit can be applied to comparative studies of polysialyltransferase expression across cell lines and primary cultures. Researchers studying tumor cell behavior, where altered polysialic acid presentation has been linked to invasion and metastatic spread, may also find the assay informative. All components ship in a single-use microplate configuration and should be handled according to standard laboratory practices for protein-based assays, with storage conditions appropriate for short-term kit use.