Human SRR ELISA Kit (HUFI06320)

Manufactured by Assay Genie, this ELISA kit targets human serine racemase (SRR), a pyridoxal-5'-phosphate-dependent enzyme that converts L-serine into D-serine, the principal endogenous co-agonist at the glycine binding site of NMDA receptors. Because D-serine modulates synaptic plasticity, excitatory neurotransmission, and glial signaling, abnormal SRR expression has been linked to schizophrenia, Alzheimer's disease, ischemic stroke, and traumatic brain injury, making quantitative SRR measurement valuable in translational neurology and psychiatry research.

The kit ships as a complete research pack with pre-coated microwell strips, lyophilized recombinant human SRR standards, biotinylated detection antibody, streptavidin-HRP, concentrated wash buffer, chromogenic TMB substrate, and stop solution. Unopened kits are kept refrigerated at 4 °C; reconstituted standards and diluted detection antibody should be aliquoted and frozen at -20 °C to limit freeze-thaw cycles and preserve binding activity.

The 96 Assays microwell plate format uses a 100 µL loading volume per well, with samples and standards run in duplicate. Assay Genie validates the kit for quantitative measurement of human SRR in blood-derived biospecimens, with intra-assay precision typically under 10% CV. The kit is intended for research use only and is not approved for diagnostic or therapeutic applications.