Human Squalene Epoxidase (SQLE) ELISA Kit

Quantify human squalene epoxidase (SQLE) levels in research samples with this immunoassay kit from Assay Genie. SQLE is a rate-limiting, FAD-dependent enzyme in cholesterol biosynthesis that catalyzes the epoxidation of squalene to 2,3-oxidosqualene within the mevalonate pathway. Aberrant SQLE expression has been investigated in hepatocellular carcinoma, breast cancer, and non-alcoholic fatty liver disease, making the assay relevant to oncology, metabolic disorder, and cardiovascular research programs.

Validated for use with tissue homogenates and cell lysates, the kit supports studies on enzyme regulation, statin pharmacology, and pathway inhibition in mammalian cell systems. Each package contains pre-coated microplate wells, calibrated reference standards, detection reagents, wash buffer, and a complete assay buffer system. Researchers should consult the enclosed protocol for component storage conditions, working dilutions, and recommended plate-reader setup specific to their sample matrix.

Intended for research use only, this absorbance-based format delivers quantitation compatible with standard microplate readers and is suited for in vitro laboratory workflows. The kit is not validated for diagnostic or clinical applications.