Human SPTBN1 (Spectrin beta chain, non-erythrocytic 1) ELISA Kit (HUFI06340)

The Spectrin beta chain, non-erythrocytic 1 (SPTBN1) protein is a key cytoskeletal scaffolding molecule that organizes membrane protein networks and supports intracellular organelle transport. This Assay Genie quantitative immunoassay enables researchers to measure SPTBN1 levels in human biological specimens using a microplate-based protocol with absorbance readout. Each kit provides sufficient reagents for 96 individual determinations, making it well matched to mid-throughput studies investigating cytoskeletal remodeling, DNA damage response pathways, and tumor biomarker discovery.

SPTBN1 has attracted significant research interest as a candidate biomarker in hepatocellular carcinoma, colorectal cancer, and certain neurological disorders, where altered expression correlates with disease progression and therapeutic outcome. Investigators apply this ELISA to profile patient-derived liquid samples, supporting translational projects that link cytoskeletal disruption to cancer cell invasion, autophagy dysregulation, and treatment resistance. The workflow integrates cleanly with standard immunochemistry pipelines: results are read on conventional plate readers and quantified against a standard curve generated from the supplied calibrators.

Each package ships with a precoated microplate, labeled detection antibody, reference standards, and substrate reagents needed to complete the full protocol. Reagent stability supports repeated use within the kit shelf life, and the procedure accommodates batched processing of clinical research cohorts. Researchers studying epithelial-mesenchymal transition, spectrin-based membrane mechanics, or SPTBN1 mutations linked to spinocerebellar ataxia type 5 will find this kit a practical tool for protein-level validation alongside their genomic and cellular assays.