Human SPOP ELISA Kit (HUFI06343)

The Human SPOP ELISA Kit from Assay Genie enables quantitative measurement of Speckle-type POZ protein in human specimens. SPOP functions as a substrate adaptor for the Cullin3-based E3 ubiquitin ligase complex, directing the proteasomal degradation of substrates including BRD4, SRC-3, ERG, and DEK. Researchers in oncology use this ELISA to investigate SPOP expression and its mutation-associated dysregulation in prostate, endometrial, and renal cell carcinomas, where recurrent SPOP mutations are well documented. Each kit provides reagents sufficient for 96 Assays run in a microplate format, supporting studies on the ubiquitin-proteasome pathway, tumor suppressor mechanisms, and biomarker discovery. Store at the temperature indicated on the packaging; allow all components to equilibrate to room temperature before use. For research use only.