Human Splicing Factor Proline And Glutamine Rich  (SFPQ) ELISA Kit

SFPQ (Splicing Factor Proline and Glutamine Rich), also known as PSF or p100, is a multifunctional nuclear protein involved in pre-mRNA splicing, paraspeckle biogenesis, and DNA damage repair. Loss of nuclear SFPQ staining is a pathological hallmark of FTLD-FUS neurodegenerative disease, while elevated levels are reported in several cancers. This Assay Genie microplate kit employs a human-specific capture antibody pair for quantitative measurement, typically requiring 50 uL sample per well. The assay is validated for serum, plasma, tissue homogenates, and other biological fluids, supporting research in neurodegeneration, oncology, and innate immunity pathways. Reagents should be refrigerated and stored protected from light.