Human Sperm surface protein Sp17 (SPA17) ELISA Kit

This sandwich ELISA kit from Assay Genie is designed for the precise measurement of human Sperm surface protein Sp17 (SPA17) in serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. The assay targets both natural and recombinant forms of the protein and is configured for human reactivity, supporting work in reproductive health, fertility, and cancer research, where SPA17 is classified as a Cancer Testis Antigen (CTA).

The kit uses a sandwich ELISA format with a detection range of 78-5000pg/mL and a sensitivity of 40.6pg/mL. According to NCBI summary information, SPA17 is a cell surface protein implicated in binding of sperm to zona pellucida, single fertilization, and spermatogenesis. It functions as a sperm surface zona pellucida binding protein that helps bind spermatozoa to the zona pellucida with high affinity, and may also function in binding zona pellucida and carbohydrates. The protein is a peripheral membrane protein located at chromosomal region 11q24.2, has calmodulin binding activity, and may form a homodimer with possible interaction with ROPN1.

For research use only.