Human SOST (Sclerostin) ELISA Kit (HUES02558)

Assay Genie's sandwich ELISA kit is designed for the quantitative measurement of Sclerostin (SOST) in human samples, including serum, plasma and other biological fluids. The assay uses a colorimetric detection method and runs in 3 h 30 min, with a sensitivity of 37.5 pg/mL and a detection range of 62.5-4000 pg/mL.

Sclerostin is described by Assay Genie as a key regulator of bone metabolism that inhibits bone formation by blocking the Wnt signaling pathway, with elevated levels associated with conditions such as osteoporosis. The kit recognizes human SOST with no significant cross-reactivity or interference between human SOST and analogues observed, and recovery is reported at 80%-120%.

The required sample volume is 100 μL and the kit is stored at 2-8°C. It is intended for research use in investigating Sclerostin's role in bone biology and exploring potential therapeutic interventions for bone-related disorders.