Human Solute Carrier Family 26,Member 4 (SLC26A4) ELISA Kit

Pendrin, the protein product of the SLC26A4 gene, is a transmembrane anion exchanger localized to inner ear epithelial cells, thyroid follicular cells, and renal tubules. This Assay Genie ELISA kit provides quantitative measurement of human pendrin in research samples, using a colorimetric readout on a microwell plate configured for 96 individual determinations per kit. Validated specimen matrices include serum samples, plasma samples, tissue homogenates, and cell lysates. Researchers studying Pendred syndrome, sensorineural hearing loss, vestibular aqueduct enlargement, iodide organification defects, or general chloride-bicarbonate transport biology can apply this immunoassay to quantify pendrin expression in cellular and tissue-extract preparations.

The kit is supplied complete with pre-coated plate wells, matched antibody reagents, calibrated pendrin reference standards, chromogenic substrate, wash concentrate, and diluent buffers sufficient for 96 tests. All components should be stored refrigerated until first use, equilibrated to room temperature before the protocol begins, and protected from prolonged light exposure. Standard ELISA procedure applies: load standards and unknown samples, incubate, wash, apply detection reagent, develop color, and read absorbance on a plate reader. Intended for research use only, the kit supports investigations into hereditary hearing-loss mechanisms, thyroid anion transport, and renal epithelial physiology.