Human Solute carrier family 2, facilitated glucose transporter member 2 (SLC2A2) ELISA Kit

A Sandwich ELISA Kit from Assay Genie designed for the quantitative measurement of human Solute carrier family 2, facilitated glucose transporter member 2 (SLC2A2), also known as Glucose transporter type 2, liver, GLUT-2 or GLUT2. The kit is reactive with human samples and is intended for research use only. Compatible sample types include serum, plasma, tissue homogenates, cell culture supernates and other biological fluids.

Reported performance characteristics include a detection range of 0.312-20 ng/mL and a sensitivity of 0.163 ng/mL, with an intra-assay CV of 7.6% and an inter-assay CV of 11.8%. Linearity across 1:2 to 1:16 dilutions (N=5) is 92-121% in serum, 84-120% in EDTA plasma, and 81-120% in heparin plasma. Recovery averages 102% for serum (range 96-108%) and 104% for plasma (range 98-110%). The assay shows specificity for natural and recombinant human SLC2A2.

SLC2A2 (UniProt P11168) is an integral plasma membrane facilitative glucose transporter that mediates the bidirectional transfer of glucose across hepatocyte plasma membranes and contributes to glucose uptake by pancreatic beta cells. The protein is a multi-pass membrane protein with a reported molecular weight of 44,702 Da, mapped to chromosomal location 3q26.1-q26.2 (NCBI Gene ID: 6514). Mutations in SLC2A2 are associated with Fanconi-Bickel syndrome and noninsulin-dependent diabetes mellitus.