Human Sodium Iodide Symporter (NIS) ELISA Kit

The sodium-iodide symporter, encoded by the SLC5A5 gene, is a transmembrane glycoprotein that mediates active iodide uptake in thyroid follicular cells, and this immunoassay kit from Assay Genie delivers quantitative measurement of that clinically important transporter. NIS is central to thyroid hormone biosynthesis, making its quantification valuable in studies of differentiated thyroid carcinoma, radioiodine therapy response, and iodide-handling disorders. Researchers also apply the kit to monitor NIS expression in extrathyroidal tissues such as lactating mammary gland, gastric mucosa, and salivary epithelium, where iodide-concentrating activity has documented physiological roles. The assay supports translational and basic research workflows, including reporter-gene imaging studies where NIS expression tracks viral vector delivery or tumor targeting in animal models. Reagents are supplied in a microplate configuration sufficient for 96 individual determinations, accommodating screening of patient cohorts, transfected cell lysates, and tissue homogenates. By providing a reproducible approach to measuring this clinically important transporter, the kit bridges fundamental studies of sodium-coupled transport with applied endocrinology and oncology research.