Human Sodium-dependent dopamine transporter (SLC6A3) ELISA Kit

From Assay Genie, this Sandwich ELISA Kit is designed for the quantitative measurement of human Sodium-dependent dopamine transporter (SLC6A3), also referred to as Solute carrier family 6 member 3, DA transporter, and DAT1. The kit detects natural and recombinant human SLC6A3 and is intended for research use only, supporting studies in the neurosciences.

Validated for human samples including serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, the assay provides a detection range of 0.312-20ng/mL with a sensitivity of 0.172ng/mL. Reported precision is an intra-assay CV of 6.6% and an inter-assay CV of 10.2%. Linearity has been characterised across dilutions of 1:2, 1:4, 1:8 and 1:16, with serum recovery averaging 104% (range 98-110%) and plasma recovery averaging 106% (range 100-112%).

SLC6A3 is a multi-pass cell membrane protein (Uniprot Q01959) that functions as an amine transporter, terminating dopamine action through high-affinity sodium-dependent reuptake into presynaptic terminals. Dysregulation of the protein is reported in research contexts related to neurological and psychiatric conditions.