Human SODD/BAG4 ELISA Kit (HUFI08443)

This kit enables quantitative measurement of BAG4 (also known as Silencer of Death Domains, SODD), a Hsp70 co-chaperone that negatively regulates TNF-receptor 1 and DR3-mediated apoptosis. The assay uses human-specific capture antibodies validated against recombinant BAG4, with reactivity limited to the human protein. Researchers studying programmed cell death, TNF signaling pathways, and stress-response chaperone biology use this kit to profile BAG4 expression in patient-derived samples and cell-based models. Published work has linked dysregulated BAG4/SODD to glioblastoma progression, breast cancer cell survival, and inflammatory cytokine responses, making it relevant for oncology and immunology laboratories investigating drug resistance mechanisms and death-receptor signaling. The microplate-based format supports high-throughput screening of clinical cohorts while minimizing consumption of precious biobank specimens. Reconstituted reagents should be stored frozen at -20°C to preserve antibody binding activity across repeated freeze-thaw cycles; the plate and standards are best kept refrigerated until first use. Each lot is validated by Assay Genie for intra- and inter-assay precision, allowing direct comparison of BAG4 levels across longitudinal studies and independent research sites.