Human SNUPN ELISA Kit (HUFI06407)

A quantitative immunoassay supporting research on human Snurportin 1, the nuclear import adaptor that mediates translocation of spliceosomal U snRNPs across the nuclear pore complex. Snurportin 1, encoded by the SNUPN gene, binds the m3G-cap of Sm-class snRNPs and, through a non-standard adaptor interface with importin-β, delivers the import cargo to the nucleoplasm where snRNP assembly, modification, and function within the spliceosome take place. Dysfunction of this pathway has been linked in published work to motor neuron phenotypes resembling spinal muscular atrophy, positioning SNUPN as a candidate gene in neuromuscular disease research and a target for interrogating RNA-processing biology in patient-derived samples. The Assay Genie kit ships as a 96 Assays reagent set, formatted for in vitro measurement of Snurportin 1 in human specimens and limited to laboratory research applications. Researchers typically process samples in line with standard ELISA practice and may pair the readout with downstream western blot or PCR analysis to confirm changes at the transcript or protein level. Reagents should be stored refrigerated at 4°C and equilibrated to room temperature before use, with standard laboratory controls and a calibration curve run alongside unknowns. The product is for research use only and has not been validated for diagnostic or clinical applications.