Human SMS (Spermine synthase) ELISA KIT (HUFI04860)

Spermine synthase (SMS) is the aminopropyltransferase enzyme that catalyzes the final step of polyamine biosynthesis, converting spermidine into spermine using decarboxylated S-adenosylmethionine as the aminopropyl donor. This Assay Genie ELISA kit provides researchers with a quantitative tool for measuring SMS protein concentrations, supporting investigations into Snyder-Robinson syndrome (caused by X-linked SMS mutations), polyamine metabolism in cancer biology, and basic cell proliferation studies. SMS is a ~45 kDa intracellular enzyme encoded on the X chromosome. The microplate is pre-coated with anti-SMS capture antibody, and bound analyte is detected using a biotinylated detection antibody and streptavidin-HRP conjugate developed with TMB substrate. Reagent components should be stored refrigerated between uses to preserve immunoreactivity.