Human SMPD2 (Sphingomyelin phosphodiesterase 2) ELISA KIT (HUFI04855)

SMPD2 encodes neutral sphingomyelinase, a hydrolase that cleaves sphingomyelin to generate ceramide and phosphorylcholine, linking membrane lipid turnover to second-messenger signaling in mammalian cells. This quantitative immunoassay from Assay Genie is configured to measure human SMPD2 protein in research specimens, supporting investigators working on sphingolipid metabolism, inflammatory signaling cascades, and ceramide-dependent apoptosis pathways.

Supplied as a complete kit with 96 Assays of ready-to-use reagents, the product supports mid-throughput studies comparing protein abundance across treatment groups, genetic backgrounds, or time-course experiments. Researchers focused on neurodegeneration, metabolic dysfunction, vascular biology, or tumor microenvironment studies frequently track SMPD2 alongside downstream ceramide quantification to understand pathway activation under different stimuli.

The platform offers a reproducible workflow for normalizing SMPD2 measurements across experimental batches, and the enclosed reagents are calibrated for research use only rather than diagnostic testing. Each plate configuration gives laboratories a flexible tool for profiling neutral sphingomyelinase dynamics in cultured cell models and tissue-derived extracts, including comparisons between wild-type and knockout phenotypes, dose-response treatments, and disease-mimicking conditions.