Human SMG6 (Telomerase-binding protein EST1A) ELISA KIT (HUFI04880)

The SMG6 target protein, also known as EST1A or Smg-6 homolog, functions as a PIN-domain endonuclease that cleaves mRNA near premature termination codons during nonsense-mediated mRNA decay (NMD) and associates with the telomerase complex to support telomere length maintenance in human cells. This Assay Genie ELISA reagent is supplied as a complete two-antibody capture-and-detection kit with pre-coated microplate wells, reference standards, biotinylated detector, and colour-development reagents sufficient for 96 Assays. Researchers apply the assay to serum or plasma specimens to quantify endogenous SMG6 levels in NMD-related and telomere-biology studies, using a 100 uL sample volume per well under standard in vitro laboratory conditions. Unopened kits should be refrigerated at 4 degrees C and protected from light to preserve antibody activity through the labelled shelf life; reconstituted components should be aliquoted to limit repeated freeze-thaw cycles.