Human SMG5 ELISA Kit (HUFI08456)

SMG5 is a critical effector of nonsense-mediated mRNA decay (NMD), functioning as part of the SMG5-SMG7 heterodimer that bridges phosphorylated UPF1 to downstream mRNA degradation machinery. Researchers investigating transcript quality control, gene expression regulation, and the molecular basis of genetic disorders caused by premature termination codons rely on quantitative measurement of SMG5 protein levels. This Assay Genie kit is validated for detection of human SMG5 in cell lysate and tissue homogenate samples, providing a reliable tool for studies in oncology, where altered NMD activity influences tumor suppressor expression, as well as neurobiology and viral infection research. The microplate format supports reproducible batch processing, and reagents should be stored refrigerated at 4°C with standard kit handling. For research use only; not intended for diagnostic applications.