Human SMARCA4 ELISA Kit (HUFI06457)

The SMARCA4 protein, also known as BRG1, is the catalytic ATPase subunit of the SWI/SNF chromatin-remodeling complex. Researchers use this quantitative immunoassay readout to study gene regulation, cell-cycle progression, and tumor biology. Loss-of-function mutations in SMARCA4 are linked to small cell carcinoma of the ovary, hypercalcemic type (SCCOHT), thoracic sarcomatoid carcinomas, and subsets of non-small cell lung cancer, making quantitative protein measurement valuable in translational oncology research.

Upon receipt, store reagents refrigerated and protect the microplate from light; reconstituted standards should be aliquoted to limit freeze-thaw cycles and preserve binding activity across runs. The Assay Genie kit supports in vitro research workflows investigating chromatin remodeler expression in human biospecimens.