Human SMAD9 ELISA Kit (HUFI06448)

SMAD9 (also known as SMAD8 or MADH6) is a receptor-regulated SMAD that mediates bone morphogenetic protein (BMP) signaling, transmitting extracellular cues into nuclear transcriptional responses. Mutations in SMAD9 have been linked to heritable pulmonary arterial hypertension, making accurate quantification of SMAD9 protein valuable in cardiovascular and pulmonary research.

This Assay Genie kit provides a quantitative immunoassay for measuring SMAD9 concentrations in research samples, with all buffers, plates, and detection reagents included in a single pack. The assay is intended for research use only and is appropriate for studies on BMP pathway activity, osteogenic differentiation, chondrogenesis, and right-heart remodeling associated with pulmonary hypertension.

Reagents should be stored at -20°C and protected from light, with shelf life of several months when handled as recommended. Thaw frozen components on ice and avoid repeated freeze-thaw cycles to preserve antibody activity.