Human Slingshot Homolog 3 (SSH3) ELISA Kit

Researchers studying actin cytoskeleton dynamics and cofilin regulation can use this ELISA Kit from Assay Genie to quantify Slingshot Homolog 3 (SSH3) phosphatase levels in human tissue homogenates. SSH3 is a dual-specificity phosphatase that reactivates cofilin by removing phosphate from Ser3, thereby driving actin filament turnover and supporting cytoskeletal remodeling in processes such as lamellipodium formation, neuronal migration, and cell motility.

The assay is supplied as a 96 assays pack and validated for in vitro use with tissue homogenate preparations from human samples. Common research applications include profiling SSH3 expression across healthy and diseased tissues, comparing phosphatase activity in cell lines with altered cofilin signaling, and investigating how SSH3 levels relate to cytoskeletal phenotypes in neuroscience, cancer biology, and developmental studies. The protocol is compatible with standard ELISA workflows and microplate reader instrumentation found in typical research laboratories.