Human SLC47A1 ELISA Kit (HUFI06464)

Built around the polyspecific organic cation exporter SLC47A1 (also called MATE1), this quantitative immunoassay from Assay Genie enables measurement of the transporter's endogenous protein levels in human research specimens. SLC47A1 drives the final step of renal tubular secretion and hepatobiliary elimination of many cationic drugs, so the assay supports studies of drug disposition, transporter pharmacogenetics, and chemical-induced regulation of cation clearance. Each kit is supplied in a format sized at 96 Assays, intended for use with circulating clinical specimens including serum-derived and plasma-derived fractions prepared under standard handling conditions. Researchers studying substrates such as metformin, cisplatin, cephalexin, or other cationic xenobiotics, as well as functional polymorphisms of the SLC47A1 gene that alter transporter activity, can apply the assay to complement pharmacokinetic and genomic readouts in vitro. Included reagents cover a complete workflow suitable for research use only.