Human SLC34A2 (Sodium-dependent phosphate transport protein 2B) ELISA Kit (HUFI06479)

SLC34A2 encodes NaPi-IIb, a type II sodium-phosphate cotransporter that mediates transcellular phosphate uptake across the intestinal brush border and is also expressed in lung alveolar epithelium. The Assay Genie immunoassay against this transporter enables quantitative measurement in human research samples, supporting investigations in mineral metabolism, pulmonary alveolar microlithiasis, and epithelial cancer biomarker discovery.

NaPi-IIb governs intestinal absorption of inorganic phosphate, and biallelic loss-of-function mutations in SLC34A2 cause pulmonary alveolar microlithiasis, a rare autosomal recessive disorder in which calcium-phosphate microliths accumulate within alveolar airspaces. Altered expression has been reported in several epithelial cancers, including ovarian and lung tumors, where it has been investigated as a tissue and serological marker. Researchers studying phosphate homeostasis, ectopic calcification, respiratory disease mechanisms, and oncology use quantitative immunoassays for this transporter to profile patient cohorts and disease models.

This 96 Assays microplate-format kit from Assay Genie uses an absorbance-based readout compatible with standard ELISA workflows, accommodating high-throughput screening and cohort-scale studies. The reagents are supplied for research use only and are intended for in vitro laboratory applications.