Human SLAMF7 ELISA Kit (HUFI06497)

This Assay Genie immunoassay kit enables quantitative measurement of Signaling Lymphocyte Activation Molecule Family Member 7 (SLAMF7), also known as CD319, CS1, or CRACC, in research samples. SLAMF7 is a type I transmembrane glycoprotein expressed on natural killer (NK) cells, B lymphocytes, activated T cells, monocytes, and plasma cells, where it modulates immune synapse formation and NK cell-mediated cytotoxicity via EAT-2 adaptor binding and immunoreceptor tyrosine-based switch motifs (ITSMs). The kit supports immunology, hematology, and oncology research into multiple myeloma, where SLAMF7 overexpression on malignant plasma cells makes it a focal point for therapeutic target studies, including monoclonal antibody research analogous to clinical anti-SLAMF7 agents. Each kit contains reagents sufficient for one microplate, along with assay-specific buffers and substrate components, all intended for research use only. Researchers investigating NK cell activation, immune cell signaling pathways, and tumor-immune interactions will find this kit applicable to studies of the SLAM receptor family and lymphocyte co-stimulation mechanisms.