Human SKP1 ELISA Kit (HUFI08480)

Quantitative measurement of human SKP1 (S-phase kinase-associated protein 1) supports research into the SCF E3 ubiquitin ligase complex, the cellular machinery that tags regulatory proteins for proteasomal destruction. The Assay Genie ELISA Kit is configured to detect SKP1 in research specimens, providing investigators with a reproducible tool for studying how this adaptor protein influences cell cycle transitions, checkpoint control, and signal-dependent protein turnover.

Because SKP1 occupies a central position in ubiquitin-dependent degradation pathways, its quantification is relevant to oncology research, where altered SCF function has been linked to uncontrolled proliferation and genomic instability. The kit also supports investigations of NF-κB signaling, since SKP1 participates in the degradation of IκBα that releases NF-κB transcription factors. Studies of developmental biology, viral pathogenesis, and immune cell signaling all draw on accurate SKP1 measurement as part of broader pathway analysis.

Each kit ships as a complete reagent set, including pre-coated microplate wells, calibrated reference standards, detection antibodies, and substrate. Researchers should aliquot reagents upon receipt and store components per the enclosed protocol to preserve activity across multiple experimental runs. The kit is designated for research use only and fits workflows in biomarker discovery, pathway interrogation, and validation studies.