Human Sirtuin 6 (SIRT6) ELISA Kit

The Sirtuin 6 protein (SIRT6) is an NAD+-dependent nuclear deacetylase implicated in DNA repair, glucose and lipid metabolism, inflammatory signaling, and cellular longevity pathways. Quantifying SIRT6 levels in clinical and experimental samples supports research into age-related disease, tumor biology, and metabolic disorders.

This Assay Genie quantitative immunoassay targets human SIRT6 and uses a colorimetric readout on a microplate to deliver 96 determinations per kit. It has been validated across multiple sample matrices, including serum, tissue homogenates, cell lysates, cell culture supernatants, and plasma specimens, giving laboratories flexibility to span biobank material through to cell-based experiments. Researchers studying histone modification, chromatin regulation, and stress-response pathways can apply the kit to monitor SIRT6 abundance across treated and untreated cohorts, time-course experiments, or comparative panels of patient-derived material.

Each kit is supplied with pre-coated plate strips and reagents sufficient to complete a full microplate. The assay follows standard ELISA workflows familiar to most laboratories, including a sequential capture and detection antibody incubation, wash steps, substrate development, and absorbance measurement. Investigators connecting SIRT6 expression to cancer progression, type 2 diabetes, cardiovascular disease, neurodegeneration, or accelerated aging will find the format helpful for higher-throughput screening.